Acta Mechanica Slovaca 2020, 24(1):14-18

Pre-clinical Testing of the Polymer Implants Enriched of Ceramic Materials with aim on Rate of Osteointegration in a Rabbit Model

Lukáš Mitrík1, Jana Klímová1, Marianna Trebuňová1, Marek Schnitzer1, Radovan Hudák1, Jozef Živčák ORCID...1, Ladislav Molnár2, Marcel Modrák1
1 Technical University of Košice, Faculty of Mechanical Engineering, Department of Biomedical Engineering, Automation and Measurement, Letná 9, Košice
2 University of Veterinary Medicine and Pharmacy in Košice, Clinic of Birds, Exotic and Free Living Animals, Komenského 73, Košice

The purpose of this paper was writing down the process of preclinical testing which consisted from usage of bioinert polymer material enriched with bioactive ceramic elements. The testing was preceded by a study of the current state and methods of implantation of polymer implants. The created samples were implanted into the animal subject femoral bone with purpose to observe the rate of osteointegration process for twelve weeks. Subsequently were the bones dissected, stripped of soft tissue and observed under stereomicroscope and submitted to histological evaluation. The whole process was detailly recorded and it is prepared for further clinical studies in field of implantation of biocompatible polymer materia

Keywords: animal testing; polymer implants; osteointegration; ceramic element

Published: March 27, 2020  Show citation

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Mitrík, L., Klímová, J., Trebuňová, M., Schnitzer, M., Hudák, R., Živčák, J., Molnár, L., & Modrák, M. (2020). Pre-clinical Testing of the Polymer Implants Enriched of Ceramic Materials with aim on Rate of Osteointegration in a Rabbit Model. Acta Mechanica Slovaca, 24(1), 14-18
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