PT Journal
AU Vranova, J
   Rosina, J
   Horak, J
   Hendrichova, M
   Kratka, K
TI Isotope-Selective Infrared Spectroscopy Reveals Pathological Changes in the Liver
SO Acta Mechanica Slovaca
PY 2010
BP 60
EP 65
VL 14
IS 2
DE 13C-methacetin; dose; cumulative dose; infrared spectroscopy; transmittance; absorbance; cirrhosis
AB An overview of new diagnostic device IRIS (Wagner Analysen Technik, Germany) is provided. This device uses the 13C stable isotope together with non-dispersive infrared selective spectroscopy for non - invasive quantification of hepatic function parameters, including kinetics (type of liver damage) and capacity (percentage of recovery yield of the liver). The short physical principle of infrared spectroscopy and acousto-optical detector of IRIS was presented. In the final section we verified the diagnostic quality of this new diagnostic device (using ANOVA) on cohort of 76 patients divided into 5 groups according to diagnosis and the various level of liver damage.
ER